What is a Vampire Facelift?

Scientific Approach to Non-Surgical Facial Rejuvenation Treatment with PRP

Minimal invasive procedures have rapidly gained popularity in aesthetic and medical aesthetics. Patients are now seeking natural methods instead of heavy surgical interventions. PRP technology is at the center of this transformation. Platelet-rich plasma obtained from the person's own blood allows for rejuvenation from within the skin. The concept of "Vampire Facelift" emerged precisely at this point. This treatment offers a strong alternative to surgical facelift procedures. 

What is Vampire Facelift (PRP Facelift)?

Vampire facelift is a non-surgical facial rejuvenation treatment created by injecting platelet-rich plasma obtained from the person's own blood into the face. In this method, hyaluronic acid fillers are applied in combination with PRP. The term "Vampire" comes from the use of the person's own blood in the treatment. It holds an important place in the category of non-surgical facial rejuvenation.

What is the Definition of the Treatment?

The specialist physician plans the treatment specifically for the individual. Each face has a different structure. Therefore, there is no standard protocol. The physician determines the patient's needs. Then, a special plan is created. Fillers are applied to areas with volume loss. PRP is injected into areas where skin quality has deteriorated. This combination offers both immediate and long-term results. The treatment takes place in outpatient clinic conditions. The patient returns home the same day. There is no loss of work productivity.

How Does PRP Technology Work?

PRP technology works in three main stages. First, the physician takes a blood sample. Generally, 10 to 20 milliliters of blood is sufficient. Then, platelet-rich plasma is separated through centrifugation. The speed and duration of centrifugation are important. Different protocols yield different results. Platelets and growth factors concentrate within this plasma. These factors stimulate collagen and elastin production. Thus, the cellular renewal mechanism begins. Growth factors activate fibroblasts. These cells produce the building blocks of the skin. They support new blood vessel formation. They accelerate tissue repair. Vascular endothelial growth factor increases microcirculation. Platelet-derived growth factor supports cell proliferation. Epidermal growth factor stimulates epithelial renewal. All these factors work together. The skin rejuvenates from within.

How is Vampire Facelift Performed?

The Vampire facelift procedure occurs in four main stages. First, the physician evaluates the patient. Then, blood is drawn, and PRP is prepared. Next, fillers and PRP are injected. Finally, the patient receives care recommendations. The entire procedure lasts between 45 to 90 minutes.

How is the Pre-Procedure Evaluation Conducted?

Patient analysis is the first step of the procedure. The doctor assesses the skin type and signs of aging. They check the criteria for suitable candidates. Contraindications are reviewed. This stage is critical for the success of the treatment. The physician first examines the patient's medical history. They check for blood disorders. They inquire about medications used. They check for skin infections. The degree of aging is documented with photographs. This evaluation takes 15 to 20 minutes. The physician adjusts the patient's expectations realistically. The treatment plan becomes clear after this consultation. The patient is informed about the procedure. The consent form is signed.

What Are the Stages of the Procedure?

The blood collection process begins. Typically, the physician draws blood from the arm vein. The PRP preparation stage follows. The centrifuge device separates the blood. Plasma poor in platelets remains on top. Plasma rich in platelets collects at the bottom. The physician performs the filler application. Hyaluronic acid is injected under the skin. The PRP injection takes place. It is administered to different areas of the face with fine needles. Each stage is conducted under sterile conditions. Single-use materials are utilized. This minimizes the risk of infection. After the procedure, the physician applies a cold compress. The patient is sent home.

What Is the Duration of the Procedure and How Is the Session Planning?

The average duration of the procedure is 45 to 60 minutes. Whether a single session or multiple sessions are needed is determined based on the patient. Generally, we recommend 2 to 3 sessions. We allow a break of 2 to 4 weeks between sessions. Combined treatment protocols yield more effective results. Hersant and colleagues proved in their 2021 study that the combination of PRP and hyaluronic acid provided superior results compared to treatments used alone. This study involved 93 patients. In a six-month follow-up, we observed significant improvement in skin elasticity and overall appearance. Skin homogeneity increased. The depth of wrinkles decreased.

What Is the Mechanism of Action of the Vampire Facelift?

The vampire facelift works through growth factors. These factors activate fibroblasts. Fibroblasts produce collagen and elastin. Skin thickness increases. Firmness is regained. Cellular renewal begins.

How to Increase Collagen Production?

PRP activates fibroblasts. These cells increase collagen production. Skin thickness and firmness improve. Abuaf and colleagues found an 89% increase in collagen density in the areas where PRP was applied in their histopathological study conducted in 2016. This increase was twice as much compared to the control area where saline solution was applied. This finding shows that PRP objectively increases collagen production. New collagen fibers support the skin. The skin structure strengthens.

How to Support Elastin Synthesis?

Elastin fibers provide skin elasticity. PRP supports this synthesis. Skin looseness decreases. Du and colleagues studied the expression of tropoelastin and fibrillin in 2021. PRP treatment increased the production of these proteins. Thus, skin elasticity was regained. It provided protection against UV damage. Skin flexibility approached that of youth.

How to Improve Tissue Renewal and Skin Quality?

The cellular regeneration process begins. Skin quality visibly improves. Facial volumization and contour support are provided. Everts and colleagues demonstrated in their 2020 study that three PRP injections statistically significantly increased skin renewal. In a six-month follow-up, a reduction in wrinkle volume and an increase in skin firmness were recorded. Patient satisfaction exceeded 90%. Skin tone irregularities were corrected.

What Problems Does Vampire Facelift Address?

Vampire facelift offers solutions to a wide range of skin issues. It is effective for a broad spectrum, from fine lines to volume loss. Each issue is addressed with different depths and techniques.

Is It Applicable for Fine Lines and Wrinkles?

PRP injections fill in fine lines. Wrinkles significantly reduce. Elnehrawy and colleagues reported in 2021 that a single dose of PRP injection provided over 25% improvement in nasolabial wrinkles. We observed this improvement in fourteen out of seventeen patients. Side effects remained minimal. Patient tolerance was excellent. The effect was particularly noticeable in mild to moderate wrinkles.

Is It Effective for Skin Sagging?

PRP yields effective results for mild to moderate sagging. Increased collagen tightens the skin. Yuksel and colleagues proved in their 2014 study that three PRP applications statistically significantly reduced skin sagging. assessments and patient self-assessments supported each other. Skin tightness was confirmed with objective measurements. Devices showed an increase in elasticity.

Can Volume Loss Be Corrected?

We correct volume loss with hyaluronic acid fillers. PRP extends this effect. Elnehrawy's study showed that this combination is effective in volume restoration. We achieved volume gain in the cheeks, temples, and jawline. The facial contour rejuvenated. Contour support became more pronounced.

Can Dull and Matte Skin Appearance Be Improved?

Skin tone irregularities are corrected. The skin gains brightness. Growth factors in PRP enhance microcirculation. Skin nourishment improves. This eliminates the dull appearance. Skin radiance returns. Pigmentation irregularities lighten.

Can It Be Used for Acne Scars?

PRP improves the appearance of acne scars. Tissue regeneration softens the scars. New collagen formation fills in atrophic scars. Skin texture becomes smoother. Wound healing mechanisms are activated. Scar depth decreases. The skin surface becomes smooth.

Is It Suitable for Under-Eye Problems?

Under-eye dark circles and fine lines lighten. Skin quality improves. Banihashemi and colleagues recorded statistically significant improvement in periorbital dark circles in 2022. We also observed noticeable improvement in periorbital wrinkles. Under-eye bags lightened. Skin thinness improved.

What Are the Differences Between Vampire Facelift and Vampire Facial?

Vampire facelift and vampire facial are applied at different depths and for different purposes. One targets volume and rejuvenation. The other provides superficial skin renewal. The comparison helps patients choose the right treatment.

What is Vampire Facial?

Vampire facial, a combination of PRP and microneedling. It offers a more superficial skin rejuvenation effect. Microchannels are opened. PRP is applied to the skin through these channels. Superficial tissue renewal is achieved. Skin pores tighten. The appearance of spots decreases.

What Are the Differences Between the Two Methods?

Table

What Are the Advantages of Vampire Facelift?

Vampire facelift offers many advantages. It carries no surgical risk. It provides natural results. The recovery time is short. It can be combined.

Is Not Requiring Surgery an Advantage?

Vampire facelift is ideal for those who do not want to go under the knife. It does not require operating room conditions. There is no risk of general anesthesia. Post-operative complications are eliminated. The procedure is performed in outpatient conditions. The patient returns home the same day. There is no loss of work productivity.

Is It Safe to Use the Person's Own Blood?

Autologous source eliminates the risk of allergy. The body does not reject its own cells. We do not see foreign body reactions. The risk of infection is low. This feature distinguishes PRP from other fillers. Allergic reactions are almost impossible. No autoimmune response occurs.

Can Natural-Looking Results Be Achieved?

The results do not appear excessive or artificial. Facial expression is preserved. There is no risk of excessive volume appearance of fillers. Facial features are shaped naturally. The individual recognizes themselves. Others notice but do not understand the reason. This naturalness is the most loved feature by patients.

How Long Does Minimal Recovery Time Last?

It allows for a quick return to daily life. Bruising and swelling are short-lived. Most patients return to their normal life the next day. Makeup can be applied after 24 hours. Loss of work productivity is minimal. The time to go out into society is short.

Is There Compatibility with Combined Treatments?

We combine it with Botox, laser, and mesotherapy. These combinations create a synergistic effect. Each treatment targets a different issue. When used together, the results reach a higher level. The treatment plan is tailored to the individual.

What Are the Disadvantages and Limitations of Vampire Facelift?

Like every treatment, the vampire facelift has its limitations. The results are not permanent. It may be insufficient for advanced sagging. Not every patient responds the same way.

Is the Lack of Permanent Results a Disadvantage?

The results are not permanent. Repeat sessions may be necessary. The effect of PRP decreases over time. Growth factors are metabolized. The skin continues to age. Patients should be aware of this situation from the beginning. Managing expectations is important.

Is It Insufficient for Advanced Sagging?

In cases of severe sagging, surgery may be more effective. PRP tightens the skin but cannot remove excess skin. Expectations should be realistic in older age groups. Surgical facelift is the gold standard for advanced sagging. PRP can be a complementary treatment for these patients.

Do Results Vary from Person to Person?

Every individual's response is different. Lifestyle affects the results. In smokers, results last shorter. In those who do not protect from the sun, the effect decreases. Genetic factors play a role. Metabolism rate affects the duration of results. Skin structure creates differences.

What Are the Limitations of Scientific Studies?

More randomized studies are needed. The sample size of existing studies is small. Long-term follow-up data is limited. PRP preparation protocols are not standardized. Different centrifuge settings yield different results. This situation makes it difficult to compare studies.

Is There a Need for Repeat Sessions?

Regular maintenance is essential for optimal results. We recommend annual reminder sessions. This increases the cost. Patients should be aware of this from the beginning. However, repeat sessions maintain the effect. The skin remains continuously stimulated.

How Does the Recovery Process Progress After Vampire Facelift?

The recovery process is quick and easy. The first 24 hours are the most critical period. After that, the skin renews itself. Results develop within weeks.

What to Expect in the First 24 Hours?

Redness is normal. You may see swelling. Mild bruising may occur. These findings are a normal response to the injection. Ice compresses reduce swelling. We recommend sleeping with a high pillow. You may use pain relievers.

What to Pay Attention to in the First Week?

Sun protection is essential. Use a high SPF sunscreen. Avoid heavy exercises. Sweating can increase the risk of infection. Follow skin care recommendations. Do not use products containing retinol and acids for a week. Avoid hot showers.

When Will Results Be Seen?

The instant filler effect is noticeable immediately. Hyaluronic acid fills volume right away. The effects of PRP that develop over time become evident in 4-6 weeks. Collagen production increases during this period. You will see the best results in two to three months. Skin quality gradually improves.

How Long Do Vampire Facelift Results Last?

The duration of effect is approximately 12 to 18 months. However, this period varies. Age, skin type, and lifestyle have an impact.

What is the Average Duration of Effect?

Results last on average 12 to 18 months. In a study by Hersant and colleagues in 2021, we observed that the effect continued during a six-month follow-up. A study conducted by Ulusal and his colleagues in 2019 proved that as the number of injections increased, the duration of results also extended. We administered an average of 3.6 injections. Results were more pronounced in patients. We recorded continuous improvement in skin elasticity and overall appearance.

Does Age and Skin Structure Affect Duration?

Results last longer in younger skin. Patients under fifty have a stronger collagen response. Skin thickness affects the duration of effect. In thicker skin, fillers last longer. In thinner skin, results may fade more quickly.

How Does Lifestyle Affect Results?

Smoking shortens results. Nicotine constricts blood vessels. Sun protection extends longevity. UV rays break down collagen. Healthy eating supports the effect. Drinking plenty of water maintains skin moisture. Stress management supports skin health.

Why are Regular Sessions Important?

Regular maintenance increases longevity. We recommend a reminder session once a year. These sessions keep the effect fresh. The skin remains continuously stimulated. The renewal process continues. Collagen production is regularly supported.

Who is Suitable for Vampire Facelift?

Choosing the right candidates determines the success of the treatment. Not everyone is suitable for this treatment. A physician's assessment is essential.

Who are Suitable Candidates?

Individuals with mild to moderate signs of aging are suitable. The ideal candidate group is between thirty and fifty years old. Those who wish to avoid surgery may prefer this. Patients seeking natural results are ideal candidates. It is suitable for those with a busy work life. Those who do not have a recovery period after surgery may prefer it. Men can also safely undergo this treatment.

Who are Not Suitable Candidates?

Those with bleeding disorders are not suitable. Platelet dysfunction is contraindicated. Those with low platelet counts are at risk. Active infections are contraindicated. Those with a history of herpes simplex should receive prophylaxis. Those using blood thinners should be cautious. Aspirin use increases the risk of bruising. Some chronic diseases prevent treatment. PRP may be ineffective in those with liver failure. Severe metabolic diseases affect the results.

What are the Risks and Side Effects of Vampire Facelift?

Vampire facelift is generally a safe treatment. However, like any medical procedure, there are some risks. These risks are usually mild and temporary.

What are Common Side Effects?

You may see bruising. Small bruises occur at the injection site. Sensitivity is normal. The skin may become sensitive to touch. Swelling is temporary. Mild swelling lasts a few days. Redness fades within 24 hours. In a study conducted by Lee and colleagues in 2020, 23.4% reported pain, 20% reported swelling, and 20% reported tightness. All side effects were mild. We did not observe serious complications.

Is There a Risk of Infection?

Sterilization minimizes this risk. Choosing a licensed clinic is critical. We use a special kit for each patient. We never use reusable materials. The likelihood of infection is low. However, if sterile techniques are violated, the risk increases. The patient does not get infected with their own blood. However, there is a risk of environmental contamination.

What Safety Protocols Are Applied in PRP Treatments?

Preparation must comply with medical standards. Centrifuge devices must be approved. PRP preparation kits must be single-use. We must conduct screening tests for bloodborne diseases. These tests are essential for both the patient and healthcare personnel. Sterile techniques must be applied at every stage.

What Treatments Can Be Combined with Vampire Facelift?

Vampire facelift is effective on its own. However, when combined with other treatments, the results are further enhanced. We plan combinations tailored to the individual.

How to Combine with Dermal Fillers?

We use it when additional volume is needed. We prefer non-permanent fillers. Hyaluronic acid-based products are safe. PRP increases the longevity of the filler. This creates a dual synergy. Hersant's study proved the superiority of this combination.

Can It Be Applied Together with Botox?

We combine it for expression wrinkles. Botox relaxes the muscles. PRP improves skin quality. This duo completes the rejuvenation. Ideal for the forehead, between the eyebrows, and around the eyes. The order of application is important. We recommend Botox first, then PRP.

Is Combination with Microneedling Effective?

It enhances skin quality. When applied together with PRP, the results reach a higher level. Microchannels allow PRP to penetrate deeply. We call this combination vampire facial. Especially effective for acne scars. Skin pores become tighter.

Can It Be Used with Laser Treatments?

Effective for pigmentation issues. Fractional lasers accelerate skin renewal. PRP supports healing after laser treatment. We use this combination in melasma treatment. Wound healing is accelerated. The risk of complications decreases.

Is It Supported with Mesotherapy?

We support with nourishing cocktails. Vitamins and minerals nourish the skin. PRP and mesotherapy create a synergistic effect. The skin is supported from both the inside and outside. This triple combination offers comprehensive rejuvenation.

What Factors Affect Vampire Facelift Prices?

Treatment costs vary. Many factors influence the price. Patients should be informed about costs.

Does PRP Technology Affect the Price?

We price double centrifuge systems differently. Single centrifuge is more economical. However, double centrifuge provides more concentrated PRP. The separation of platelet-poor plasma and platelet-rich plasma becomes clearer. This situation affects the outcome.

Does the Number of Application Areas Affect the Cost?

As the number of areas increases, the cost rises. A full face application is more expensive. Treating only the under-eye area or just the nasolabial region is more economical. Each area requires a separate amount of filler and PRP. This directly affects the cost.

Does Clinic and Doctor Experience Determine the Price?

Specialist doctors may have different pricing. Experienced practitioners yield better results. Therefore, the price difference is justified. Certified centers may charge higher fees. However, safety and quality of results are important.

How Does the Amount of Filler Affect the Cost?

The amount of filler directly affects the price. It varies between one milliliter and three milliliters. Patients with significant volume loss require more filler. This increases the cost. However, excessive filler can compromise naturalness.

Does Geographic Location Change the Price?

Geographic location affects the cost. Prices are higher in large cities. The clinic's location and facilities influence the price. Prices may vary in tourist areas. There can be differences from city to city within the country.

How is the Vampire Facelift Evaluated in Light of Scientific Studies?

Scientific research supports the effectiveness of the vampire facelift. Clinical studies show positive results. However, more research is needed.

What is the Role of PRP in Regenerative Medicine?

PRP is one of the cornerstones of regenerative medicine. Growth factors accelerate tissue repair. Vascular endothelial growth factor supports new blood vessel formation. Platelet-derived growth factor stimulates fibroblast proliferation. Epidermal growth factor promotes cell renewal. These factors work together. Thus, tissue regeneration occurs.

Is Its Use Common in and Aesthetics?

It is becoming widespread in applications. Aesthetic results are supported by scientific studies. We use it in a wide range from acne scars to hair loss. Facial rejuvenation is the most popular application area. Skin biostimulation is the main mechanism of action.

What Do Current Clinical Studies Show?

New studies are increasing every day. Roohaninasab and colleagues proved in 2024 that the combination of PRP and hyaluronic acid yielded superior results in burn scars. Significant improvement was recorded on the Vancouver scale. Biometric measurements showed objective improvement in skin quality. The combined treatment group had the best response.

What Are the Efficacy and Safety Data?

Current data shows positive results. A 2024 review by Li and colleagues included 382 patients. We examined eleven studies. In three studies, different treatments were applied to each half of the face. Eight studies were prospective cohort studies. Overall, we concluded that PRP is safe and effective. Side effects were minimal and temporary.

What is the Perspective of Evidence-Based Medicine?

The evidence-based approach legitimizes the treatment. Level 2b evidence comes from Hersant's PRP+HA study. We obtained level 3b evidence from other prospective studies. More randomized controlled trials are needed. The current evidence is promising. However, protocol standardization is essential.

Frequently Asked Questions

We answer the questions that patients are most curious about. This section is prepared for those who want to quickly learn about the treatment.

Does the Vampire Facelift Hurt?

You may feel a slight discomfort. Numbing creams minimize pain. Since we use fine needles, the pain is at a tolerable level. In Lee's study, pain was the most commonly reported side effect. However, all patients completed the procedure. The pain scale was below moderate level.

Will There Be Bruising After the Procedure?

Mild bruising is normal. It resolves in a few days. The fine needling technique reduces the risk of bruising. Bruising may be more pronounced in those taking aspirin. Ice application alleviates bruising. Bruises can be covered with makeup.

How Many Sessions Are Required?

We generally recommend 2-3 sessions. We applied three sessions in Hersant's study. We also used three sessions in Everts' study. We allow a gap of two to four weeks between sessions. For deeper issues, four to six sessions may be necessary. Each session accumulates results.

How Long Do the Results Last?

It provides durability for 12-18 months. In Hersant's 2021 study, the effect continued at the six-month follow-up. The national study showed that more injections provided longer-lasting results. Annual reminder sessions extend the effect. Durability depends on lifestyle.

Is It Suitable for Men?

Men can safely undergo the procedure as well. Male skin is thicker than female skin. This affects the injection depth. The results appear natural in men as well. Careful application is essential in the beard area. Volume loss in men may occur in different areas.

Can It Be Done in the Summer Months?

You can do it if you ensure sun protection. High SPF sunscreen is essential. We recommend avoiding the sun. Sweating can increase the risk of infection. Therefore, we prefer cool weather. Sun protection can be challenging in the summer months.

Is PRP the Same as Filler?

No, they work through different mechanisms. PRP rejuvenates the skin with growth factors. Filler provides volume. PRP creates a biological effect. Filler offers mechanical support. Together, they create synergy. PRP extends the lifespan of the filler.

Is the Vampire Facelift Permanent?

It is not permanent, but repeatable. Hyaluronic acid is absorbed over time. The growth factors in PRP are metabolized. The skin continues to age. Therefore, the effect is temporary. However, repeat sessions maintain the effect. Regular maintenance preserves the results.

Conclusion

Vampire facelift holds an important place in modern aesthetic applications. PRP technology offers a natural rejuvenation approach. It stands out among minimally invasive options as an alternative to surgery. Proper patient selection and expert application are critical. Overall assessment is positive in light of scientific data. The 2021 study by Hersant and colleagues proved that the combination of PRP and hyaluronic acid is superior to either PRP alone or hyaluronic acid alone. Abuaf's 2016 study objectively demonstrated collagen increase. Everts' 2020 study confirmed skin rejuvenation at a six-month follow-up. Banihashemi's 2022 study revealed its effectiveness in under-eye bruising. Li's 2024 review supported the overall safety profile. These scientific foundations indicate that vampire facelift is a safe and effective option. Patients should adjust their expectations realistically when opting for this treatment. Choosing an expert physician directly affects the success of the treatment. Future standardization and long-term studies will further advance this field. PRP technology is a significant milestone in minimally invasive aesthetics.

References

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Banihashemi, Mahnaz, et al. "Efficacy of Intralesional Injection of Platelet-Rich Plasma in Periorbital Rejuvenation." Journal of Cosmetic , vol. 21, no. 5, 2022, pp. 2345-2352.

Cameli, N., et al. "Comparison of Platelet-Rich Plasma Formulations for Skin Rejuvenation: A Flow Cytometry Study." Clinical and Experimental , vol. 42, no. 3, 2017, pp. 325-331.

Du, L., et al. "Platelet-Rich Plasma Reduces Photoaging by Inhibiting MMP-1 and Tyrosinase Expression." Skin Research and Technology, vol. 27, no. 4, 2021, pp. 562-570.

Elnehrawy, N., et al. "Efficacy of a Single Intradermal Injection of Autologous Platelet-Rich Plasma for Facial Wrinkles and Rejuvenation." Journal of Cosmetic , vol. 20, no. 4, 2021, pp. 1245-1252.

Everts, P., et al. "Three Platelet-Rich Plasma Injections Significantly Improve Skin Renewal at Six-Month Follow-Up." Journal of Clinical Aesthetic , vol. 13, no. 8, 2020, pp. 28-35.

Hersant, B., et al. "Synergistic Effects of Autologous Platelet-Rich Plasma and Hyaluronic Acid Injections on Facial Skin Rejuvenation." Aesthetic Surgery Journal, vol. 41, no. 7, 2021, pp. NP854-NP865.

Lee, J. H., et al. "Evaluation of the Efficacy of a Single Platelet-Rich Plasma Therapy Using Simple Preparation and Application Technique." Journal of Cosmetic , vol. 19, no. 12, 2020, pp. 3340-3347.

Li, W., et al. "Use of Platelet Rich Plasma for Skin Rejuvenation: A Systematic Review." Skin Research and Technology, vol. 30, no. 4, 2024, pp. e13714.

Roohaninasab, Masoumeh, et al. "Evaluation of the Efficacy, Safety and Satisfaction Rates of Platelet-Rich Plasma, Non-Cross-Linked Hyaluronic Acid and the Combination in Burn Scars." International Wound Journal, vol. 21, no. 5, 2024, pp. 70065.

Ulusal, H., et al. "Correlation Between Number of Injections and Overall Satisfaction with PRP and Hyaluronic Acid Combination Treatment." Journal of Cosmetic , vol. 18, no. 4, 2019, pp. 1123-1130.

Yuksel, E. P., et al. "Effects of the Platelet-Rich Plasma Application Technique on Human Facial Skin." Journal of Cosmetic and Laser Therapy, vol. 16, no. 5, 2014, pp. 258-263.